2q17

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:27, 17 October 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Formylglycine Generating Enzyme from Streptomyces coelicolor==
==Formylglycine Generating Enzyme from Streptomyces coelicolor==
-
<StructureSection load='2q17' size='340' side='right' caption='[[2q17]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='2q17' size='340' side='right'caption='[[2q17]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2q17]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Strco Strco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q17 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q17 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2q17]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q17 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q17 OCA], [http://pdbe.org/2q17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q17 RCSB], [http://www.ebi.ac.uk/pdbsum/2q17 PDBsum]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q17 OCA], [https://pdbe.org/2q17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q17 RCSB], [https://www.ebi.ac.uk/pdbsum/2q17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q17 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FGE_STRCO FGE_STRCO] Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile.<ref>PMID:18390551</ref> <ref>PMID:25931126</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/2q17_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/2q17_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q17 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 29: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Strco]]
+
[[Category: Large Structures]]
-
[[Category: Ballister, E R]]
+
[[Category: Ballister ER]]
-
[[Category: Berger, J M]]
+
[[Category: Berger JM]]
-
[[Category: Bertozzi, C R]]
+
[[Category: Bertozzi CR]]
-
[[Category: Breidenbach, M A]]
+
[[Category: Breidenbach MA]]
-
[[Category: Carlson, B L]]
+
[[Category: Carlson BL]]
-
[[Category: Gilmore, S A]]
+
[[Category: Gilmore SA]]
-
[[Category: King, D S]]
+
[[Category: King DS]]
-
[[Category: Skordalakes, E]]
+
[[Category: Skordalakes E]]
-
[[Category: Fge]]
+
-
[[Category: Formylglycine]]
+
-
[[Category: Sulfatase]]
+
-
[[Category: Unknown function]]
+

Current revision

Formylglycine Generating Enzyme from Streptomyces coelicolor

PDB ID 2q17

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2q17"
Personal tools