1ir6

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==Crystal structure of exonuclease RecJ bound to manganese==
==Crystal structure of exonuclease RecJ bound to manganese==
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<StructureSection load='1ir6' size='340' side='right' caption='[[1ir6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='1ir6' size='340' side='right'caption='[[1ir6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ir6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IR6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ir6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IR6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ir6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ir6 OCA], [http://pdbe.org/1ir6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ir6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ir6 PDBsum], [http://www.topsan.org/Proteins/RSGI/1ir6 TOPSAN]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ir6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ir6 OCA], [https://pdbe.org/1ir6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ir6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ir6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ir6 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ir6 TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RECJ_THET8 RECJ_THET8] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.<ref>PMID:21087930</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/1ir6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/1ir6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ir6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Exonuclease|Exonuclease]]
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*[[Exonuclease 3D structures|Exonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
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[[Category: Large Structures]]
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[[Category: Fukuyama, K]]
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[[Category: Thermus thermophilus]]
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[[Category: Kakuta, Y]]
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[[Category: Fukuyama K]]
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[[Category: Masui, R]]
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[[Category: Kakuta Y]]
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[[Category: Structural genomic]]
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[[Category: Masui R]]
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[[Category: Yamagata, A]]
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[[Category: Yamagata A]]
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[[Category: Dna recombination]]
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[[Category: Dna repair]]
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[[Category: Hydrolase]]
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[[Category: Manganese]]
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[[Category: Nuclease]]
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[[Category: Rsgi]]
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[[Category: Single-stranded dna]]
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[[Category: Two domains interconnected by alpha-helix]]
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Current revision

Crystal structure of exonuclease RecJ bound to manganese

PDB ID 1ir6

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