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2b0c
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==The crystal structure of the putative phosphatase from Escherichia coli== | ==The crystal structure of the putative phosphatase from Escherichia coli== | ||
| - | <StructureSection load='2b0c' size='340' side='right' caption='[[2b0c]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='2b0c' size='340' side='right'caption='[[2b0c]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2b0c]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2b0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B0C FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G1P:ALPHA-D-GLUCOSE-1-PHOSPHATE'>G1P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b0c OCA], [https://pdbe.org/2b0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b0c RCSB], [https://www.ebi.ac.uk/pdbsum/2b0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b0c ProSAT], [https://www.topsan.org/Proteins/MCSG/2b0c TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/YIHX_ECOLI YIHX_ECOLI] Catalyzes the dephosphorylation of alpha-D-glucose-1-phosphate (Glu1P) and has no activity with the beta form. In addition, YihX has phosphatase activity against sugar-phosphate and pyridoxal phosphate (PLP) and low beta-phosphoglucomutase activity.<ref>PMID:15808744</ref> <ref>PMID:16990279</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/2b0c_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/2b0c_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b0c ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Edwards A]] |
| - | [[Category: | + | [[Category: Joachimiak A]] |
| - | [[Category: Savchenko | + | [[Category: Savchenko A]] |
| - | [[Category: Skarina | + | [[Category: Skarina T]] |
| - | [[Category: Zhang | + | [[Category: Zhang R]] |
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Current revision
The crystal structure of the putative phosphatase from Escherichia coli
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