2qfe

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==Distal C2-Like Domain of Human Calpain-7==
==Distal C2-Like Domain of Human Calpain-7==
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<StructureSection load='2qfe' size='340' side='right' caption='[[2qfe]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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<StructureSection load='2qfe' size='340' side='right'caption='[[2qfe]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qfe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QFE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qfe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QFE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAPN7, PALBH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qfe OCA], [http://pdbe.org/2qfe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qfe RCSB], [http://www.ebi.ac.uk/pdbsum/2qfe PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qfe OCA], [https://pdbe.org/2qfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qfe RCSB], [https://www.ebi.ac.uk/pdbsum/2qfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qfe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CAN7_HUMAN CAN7_HUMAN]] Calcium-regulated non-lysosomal thiol-protease (By similarity).
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[https://www.uniprot.org/uniprot/CAN7_HUMAN CAN7_HUMAN] Calcium-regulated non-lysosomal thiol-protease (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/2qfe_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/2qfe_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qfe ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Calpain|Calpain]]
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*[[Calpain 3D structures|Calpain 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A]]
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[[Category: Arrowsmith CH]]
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[[Category: Cuerrier, D]]
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[[Category: Bochkarev A]]
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[[Category: Dhe-Paganon, S]]
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[[Category: Cuerrier D]]
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[[Category: Edwards, A M]]
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[[Category: Dhe-Paganon S]]
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[[Category: Ravulapalli, R]]
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[[Category: Edwards AM]]
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[[Category: Walker, J R]]
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[[Category: Ravulapalli R]]
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[[Category: Weigelt, J]]
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[[Category: Walker JR]]
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[[Category: C2-like domain]]
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[[Category: Weigelt J]]
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[[Category: Hydrolase]]
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[[Category: Nuclear protein]]
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[[Category: Protease]]
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[[Category: Thiol protease]]
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Current revision

Distal C2-Like Domain of Human Calpain-7

PDB ID 2qfe

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