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2g8m

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[[Image:2g8m.gif|left|200px]]
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#REDIRECT [[4gev]] This PDB entry is obsolete and replaced by 4gev
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{{Structure
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|PDB= 2g8m |SIZE=350|CAPTION= <scene name='initialview01'>2g8m</scene>, resolution 1.30&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=UMP:2&#39;-DEOXYURIDINE+5&#39;-MONOPHOSPHATE'>UMP</scene> and <scene name='pdbligand=CB3:10-PROPARGYL-5,8-DIDEAZAFOLIC ACID'>CB3</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45]
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|GENE= thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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}}
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'''Escherichia coli thymidylate synthase Y209W in complex with substrate, dUMP, and a cofactor analog, CB3717'''
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==About this Structure==
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2G8M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8M OCA].
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[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Thymidylate synthase]]
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[[Category: Lee, T T.]]
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[[Category: Newby, Z.]]
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[[Category: Stroud, R M.]]
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[[Category: CB3]]
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[[Category: UMP]]
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[[Category: alpha/beta protein]]
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[[Category: antifolate]]
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[[Category: beta sheet]]
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[[Category: dump]]
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[[Category: dump binding site mutant]]
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[[Category: ternary complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:09:32 2008''
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Current revision

  1. REDIRECT 4gev This PDB entry is obsolete and replaced by 4gev

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