2hxs

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[[Image:2hxs.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of Rab28A GTPase in the Inactive (GDP-3'P-Bound) Form==
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|PDB= 2hxs |SIZE=350|CAPTION= <scene name='initialview01'>2hxs</scene>, resolution 1.10&Aring;
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<StructureSection load='2hxs' size='340' side='right'caption='[[2hxs]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=G3D:GUANOSINE-3&#39;-MONOPHOSPHATE-5&#39;-DIPHOSPHATE'>G3D</scene>
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<table><tr><td colspan='2'>[[2hxs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HXS FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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|GENE= RAB28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G3D:GUANOSINE-3-MONOPHOSPHATE-5-DIPHOSPHATE'>G3D</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxs OCA], [https://pdbe.org/2hxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hxs RCSB], [https://www.ebi.ac.uk/pdbsum/2hxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hxs ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/RAB28_HUMAN RAB28_HUMAN] Cone rod dystrophy. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23746546</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/RAB28_HUMAN RAB28_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hxs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hxs ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of Rab28A GTPase in the Inactive (GDP-Bound) Form'''
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==See Also==
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2HXS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXS OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Dominguez, R.]]
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[[Category: Dominguez R]]
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[[Category: Ferron, F.]]
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[[Category: Lee SH]]
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[[Category: Kerff, F.]]
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[[Category: Li Y]]
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[[Category: Lee, S H.]]
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[[Category: Li, Y.]]
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[[Category: G3D]]
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[[Category: MG]]
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[[Category: gtpase]]
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[[Category: rab]]
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[[Category: ra]]
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[[Category: signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:17:58 2008''
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Current revision

Crystal Structure of Rab28A GTPase in the Inactive (GDP-3'P-Bound) Form

PDB ID 2hxs

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