2r5b

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==Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7==
==Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7==
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<StructureSection load='2r5b' size='340' side='right' caption='[[2r5b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2r5b' size='340' side='right'caption='[[2r5b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2r5b]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R5B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2r5b]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAS:D-ASPARTIC+ACID'>DAS</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=DGN:D-GLUTAMINE'>DGN</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAS:D-ASPARTIC+ACID'>DAS</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=DGN:D-GLUTAMINE'>DGN</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5b OCA], [https://pdbe.org/2r5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5b RCSB], [https://www.ebi.ac.uk/pdbsum/2r5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5b ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r3c|2r3c]], [[2r5d|2r5d]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5b OCA], [http://pdbe.org/2r5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r5b RCSB], [http://www.ebi.ac.uk/pdbsum/2r5b PDBsum]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Gp41|Gp41]]
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*[[Gp41 3D Structures|Gp41 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Heroux, A]]
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[[Category: Large Structures]]
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[[Category: Hill, C P]]
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[[Category: Synthetic construct]]
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[[Category: Kay, M S]]
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[[Category: Heroux A]]
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[[Category: VanDemark, A P]]
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[[Category: Hill CP]]
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[[Category: Welch, B]]
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[[Category: Kay MS]]
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[[Category: Hiv]]
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[[Category: VanDemark AP]]
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[[Category: Pie]]
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[[Category: Welch B]]
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[[Category: Viral entry]]
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[[Category: Viral protein-inhibitor complex]]
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Current revision

Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7

PDB ID 2r5b

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