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1rz8

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==CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B==
==CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B==
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<StructureSection load='1rz8' size='340' side='right' caption='[[1rz8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='1rz8' size='340' side='right'caption='[[1rz8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1rz8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZ8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1rz8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RZ8 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rz7|1rz7]], [[1rzf|1rzf]], [[1rzg|1rzg]], [[1rzi|1rzi]], [[1rzj|1rzj]], [[1rzk|1rzk]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz8 OCA], [http://pdbe.org/1rz8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rz8 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz8 OCA], [https://pdbe.org/1rz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rz8 RCSB], [https://www.ebi.ac.uk/pdbsum/1rz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rz8 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rz/1rz8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rz/1rz8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rz8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Sandbox 20009|Sandbox 20009]]
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*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Choe, H]]
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[[Category: Large Structures]]
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[[Category: Dimitrov, D S]]
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[[Category: Choe H]]
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[[Category: Farzan, M]]
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[[Category: Dimitrov DS]]
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[[Category: Hendrickson, W A]]
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[[Category: Farzan M]]
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[[Category: Huang, C C]]
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[[Category: Hendrickson WA]]
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[[Category: Kwong, P D]]
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[[Category: Huang CC]]
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[[Category: Majeed, S]]
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[[Category: Kwong PD]]
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[[Category: Moore, M J]]
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[[Category: Majeed S]]
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[[Category: Phogat, S]]
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[[Category: Moore MJ]]
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[[Category: Robinson, J]]
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[[Category: Phogat S]]
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[[Category: Sodroski, J]]
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[[Category: Robinson J]]
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[[Category: Venturi, M]]
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[[Category: Sodroski J]]
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[[Category: Wyatt, R]]
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[[Category: Venturi M]]
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[[Category: Zhang, M Y]]
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[[Category: Wyatt R]]
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[[Category: Antibody]]
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[[Category: Zhang M-Y]]
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[[Category: Cd4i]]
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[[Category: Gp120]]
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[[Category: Hiv-1]]
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[[Category: Immune system]]
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[[Category: Tyrosine sulfation]]
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[[Category: Vh-gene usage]]
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Current revision

CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B

PDB ID 1rz8

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