This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2l6a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:39, 15 May 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Three-dimensional structure of the N-terminal effector PYRIN domain of NLRP12==
==Three-dimensional structure of the N-terminal effector PYRIN domain of NLRP12==
-
<StructureSection load='2l6a' size='340' side='right' caption='[[2l6a]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2l6a' size='340' side='right'caption='[[2l6a]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2l6a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L6A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2L6A FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2l6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L6A FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NLRP12, NALP12, PYPAF7, RNO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l6a OCA], [http://pdbe.org/2l6a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2l6a RCSB], [http://www.ebi.ac.uk/pdbsum/2l6a PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l6a OCA], [https://pdbe.org/2l6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l6a RCSB], [https://www.ebi.ac.uk/pdbsum/2l6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l6a ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/NAL12_HUMAN NAL12_HUMAN]] NLRP12-associated hereditary periodic fever syndrome. The disease is caused by mutations affecting the gene represented in this entry.
+
[https://www.uniprot.org/uniprot/NAL12_HUMAN NAL12_HUMAN] NLRP12-associated hereditary periodic fever syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NAL12_HUMAN NAL12_HUMAN]] May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.
+
[https://www.uniprot.org/uniprot/NAL12_HUMAN NAL12_HUMAN] May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 20:
</div>
</div>
<div class="pdbe-citations 2l6a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2l6a" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Pyrin domain|Pyrin domain]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Peti, W]]
+
[[Category: Large Structures]]
-
[[Category: Pinheiro, A S]]
+
[[Category: Peti W]]
-
[[Category: Death domain]]
+
[[Category: Pinheiro AS]]
-
[[Category: Nlrp12]]
+
-
[[Category: Pyrin]]
+
-
[[Category: Signaling protein]]
+

Current revision

Three-dimensional structure of the N-terminal effector PYRIN domain of NLRP12

PDB ID 2l6a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2l6a"
Personal tools