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2pyz

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[[Image:2pyz.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of the complex of proteinase K with auramine at 1.8A resolution==
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|PDB= 2pyz |SIZE=350|CAPTION= <scene name='initialview01'>2pyz</scene>, resolution 1.79&Aring;
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<StructureSection load='2pyz' size='340' side='right'caption='[[2pyz]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene> and <scene name='pdbligand=AU4:4,4&#39;-(AMINOMETHYLENE)BIS(N,N-DIMETHYLANILINE)'>AU4</scene>
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<table><tr><td colspan='2'>[[2pyz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PYZ FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU4:4,4-(AMINOMETHYLENE)BIS(N,N-DIMETHYLANILINE)'>AU4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pyz OCA], [https://pdbe.org/2pyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pyz RCSB], [https://www.ebi.ac.uk/pdbsum/2pyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pyz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2pyz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pyz ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of the complex of proteinase K with auramine at 1.8A resolution'''
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==See Also==
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*[[Proteinase 3D structures|Proteinase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2PYZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PYZ OCA].
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[[Category: Large Structures]]
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[[Category: Engyodontium album]]
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[[Category: Parengyodontium album]]
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[[Category: Peptidase K]]
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[[Category: Bhushan A]]
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[[Category: Single protein]]
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[[Category: Kaur P]]
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[[Category: Bhushan, A.]]
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[[Category: Sharma S]]
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[[Category: Kaur, P.]]
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[[Category: Singh AK]]
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[[Category: Sharma, S.]]
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[[Category: Singh N]]
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[[Category: Singh, A K.]]
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[[Category: Singh TP]]
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[[Category: Singh, N.]]
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[[Category: Sinha M]]
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[[Category: Singh, T P.]]
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[[Category: Sinha, M.]]
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[[Category: AU4]]
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[[Category: CA]]
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[[Category: NO3]]
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[[Category: enzyme activity]]
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[[Category: inhibition]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:41:48 2008''
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Current revision

Crystal structure of the complex of proteinase K with auramine at 1.8A resolution

PDB ID 2pyz

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