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2on5

From Proteopedia

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==Structure of NaGST-2==
==Structure of NaGST-2==
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<StructureSection load='2on5' size='340' side='right' caption='[[2on5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='2on5' size='340' side='right'caption='[[2on5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2on5]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_hookworm Human hookworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ON5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ON5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2on5]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Necator_americanus Necator americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ON5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ON5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2on7|2on7]], [[1tw9|1tw9]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2on5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2on5 OCA], [http://pdbe.org/2on5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2on5 RCSB], [http://www.ebi.ac.uk/pdbsum/2on5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2on5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2on5 OCA], [https://pdbe.org/2on5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2on5 RCSB], [https://www.ebi.ac.uk/pdbsum/2on5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2on5 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D3U1A6_NECAM D3U1A6_NECAM]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2on5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2on5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2on5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Glutathione S-transferase|Glutathione S-transferase]]
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human hookworm]]
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[[Category: Large Structures]]
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[[Category: Asojo, O A]]
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[[Category: Necator americanus]]
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[[Category: Goud, G]]
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[[Category: Asojo OA]]
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[[Category: Homma, H]]
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[[Category: Goud G]]
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[[Category: Hotez, P J]]
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[[Category: Homma H]]
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[[Category: Ngamelue, M]]
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[[Category: Hotez PJ]]
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[[Category: Zhan, B]]
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[[Category: Ngamelue M]]
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[[Category: Gst]]
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[[Category: Zhan B]]
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[[Category: Hookworm]]
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[[Category: Necator]]
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[[Category: Transferase]]
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Current revision

Structure of NaGST-2

PDB ID 2on5

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