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1xy2

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==CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING==
==CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING==
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<StructureSection load='1xy2' size='340' side='right' caption='[[1xy2]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='1xy2' size='340' side='right'caption='[[1xy2]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xy2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XY2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xy2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XY2 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPR:2-MERCAPTO-PROPION+ALDEHYDE'>MPR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy2 OCA], [http://pdbe.org/1xy2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xy2 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy2 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPR:2-MERCAPTO-PROPION+ALDEHYDE'>MPR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy2 OCA], [https://pdbe.org/1xy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xy2 RCSB], [https://www.ebi.ac.uk/pdbsum/1xy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xy2 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NEU1_BOVIN NEU1_BOVIN] Neurophysin 1 specifically binds oxytocin. Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Blundell, T L]]
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[[Category: Large Structures]]
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[[Category: Cooper, S]]
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[[Category: Blundell TL]]
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[[Category: Pitts, J E]]
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[[Category: Cooper S]]
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[[Category: Tickle, I J]]
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[[Category: Pitts JE]]
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[[Category: Wood, S P]]
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[[Category: Tickle IJ]]
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[[Category: Hormone]]
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[[Category: Wood SP]]

Current revision

CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING

PDB ID 1xy2

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