This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2qvw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:10, 26 July 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of Giardia Dicer refined against twinned data==
==Structure of Giardia Dicer refined against twinned data==
-
<StructureSection load='2qvw' size='340' side='right' caption='[[2qvw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+
<StructureSection load='2qvw' size='340' side='right'caption='[[2qvw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2qvw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Giain Giain]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2qvw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVW FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ffl|2ffl]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_III Ribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.3 3.1.26.3] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvw OCA], [https://pdbe.org/2qvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvw RCSB], [https://www.ebi.ac.uk/pdbsum/2qvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvw ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvw OCA], [http://pdbe.org/2qvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qvw RCSB], [http://www.ebi.ac.uk/pdbsum/2qvw PDBsum]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DCL_GIAIC DCL_GIAIC] Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs.<ref>PMID:16410517</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Giain]]
+
[[Category: Giardia intestinalis]]
-
[[Category: Ribonuclease III]]
+
[[Category: Large Structures]]
-
[[Category: Doudna, J A]]
+
[[Category: Doudna JA]]
-
[[Category: MacRae, I J]]
+
[[Category: MacRae IJ]]
-
[[Category: Dicer]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Pseudo-merohedral twin]]
+
-
[[Category: Rnai]]
+

Current revision

Structure of Giardia Dicer refined against twinned data

PDB ID 2qvw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qvw"
Personal tools