1j5s

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[[Image:1j5s.gif|left|200px]]
 
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{{Structure
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==Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution==
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|PDB= 1j5s |SIZE=350|CAPTION= <scene name='initialview01'>1j5s</scene>, resolution 2.85&Aring;
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<StructureSection load='1j5s' size='340' side='right'caption='[[1j5s]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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|SITE= <scene name='pdbsite=SA:Active+Site+At+H30,+H32,+W366,+D397.+These+Residues+Coor+...'>SA</scene>, <scene name='pdbsite=SB:Active+Site+At+H30,+H32,+W366,+D397.+These+Residues+Coor+...'>SB</scene> and <scene name='pdbsite=SC:Active+Site+At+H30,+H32,+W366,+D397.+These+Residues+Coor+...'>SC</scene>
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1j5s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J5S FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucuronate_isomerase Glucuronate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.12 5.3.1.12] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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|GENE= TM0064 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j5s OCA], [https://pdbe.org/1j5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j5s RCSB], [https://www.ebi.ac.uk/pdbsum/1j5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j5s ProSAT], [https://www.topsan.org/Proteins/JCSG/1j5s TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK02925 PRK02925], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1904 UxaC]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j5s OCA], [http://www.ebi.ac.uk/pdbsum/1j5s PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1j5s RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/UXAC_THEMA UXAC_THEMA]
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== Evolutionary Conservation ==
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'''Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/1j5s_consurf.spt"</scriptWhenChecked>
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1J5S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J5S OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution., Schwarzenbacher R, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McMullan D, McPhillips TM, Miller MA, Miller MD, Morse A, Moy K, Ouyang J, Robb A, Rodrigues K, Selby TL, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang X, West B, Wolf G, Hodgson KO, Wooley J, Wilson IA, Proteins. 2003 Oct 1;53(1):142-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12945057 12945057]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j5s ConSurf].
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[[Category: Glucuronate isomerase]]
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<div style="clear:both"></div>
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[[Category: Single protein]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: jcsg]]
 
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[[Category: joint center for structural genomic]]
 
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[[Category: protein structure initiative]]
 
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[[Category: psi]]
 
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[[Category: structural genomic]]
 
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[[Category: tm0064]]
 
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[[Category: uronate isomerase]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 25 23:24:12 2008''
 

Current revision

Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution

PDB ID 1j5s

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