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2hr9

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==Solution structure of human translationally controlled tumor protein==
==Solution structure of human translationally controlled tumor protein==
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<StructureSection load='2hr9' size='340' side='right' caption='[[2hr9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2hr9' size='340' side='right'caption='[[2hr9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2hr9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1y41 1y41]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HR9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2hr9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1y41 1y41]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HR9 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hr9 OCA], [http://pdbe.org/2hr9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hr9 RCSB], [http://www.ebi.ac.uk/pdbsum/2hr9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hr9 OCA], [https://pdbe.org/2hr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hr9 RCSB], [https://www.ebi.ac.uk/pdbsum/2hr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hr9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TCTP_HUMAN TCTP_HUMAN]] Involved in calcium binding and microtubule stabilization.
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[https://www.uniprot.org/uniprot/TCTP_HUMAN TCTP_HUMAN] Involved in calcium binding and microtubule stabilization.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hr/2hr9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hr/2hr9_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hr9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Feng, Y]]
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[[Category: Large Structures]]
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[[Category: Liu, D]]
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[[Category: Feng Y]]
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[[Category: Wang, J]]
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[[Category: Liu D]]
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[[Category: Yao, H]]
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[[Category: Wang J]]
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[[Category: Apoptosis]]
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[[Category: Yao H]]
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[[Category: Metal binding protein]]
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[[Category: Tumor protein]]
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Current revision

Solution structure of human translationally controlled tumor protein

PDB ID 2hr9

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