1zdk

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==STRUCTURE OF BACTERIOPHAGE COAT PROTEIN-LOOP RNA COMPLEX==
==STRUCTURE OF BACTERIOPHAGE COAT PROTEIN-LOOP RNA COMPLEX==
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<StructureSection load='1zdk' size='340' side='right' caption='[[1zdk]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
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<StructureSection load='1zdk' size='340' side='right'caption='[[1zdk]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zdk]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZDK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZDK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zdk]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZDK FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zdk OCA], [http://pdbe.org/1zdk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zdk RCSB], [http://www.ebi.ac.uk/pdbsum/1zdk PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zdk OCA], [https://pdbe.org/1zdk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zdk RCSB], [https://www.ebi.ac.uk/pdbsum/1zdk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zdk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
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[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zd/1zdk_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zd/1zdk_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zdk ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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<div class="pdbe-citations 1zdk" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1zdk" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacteriophage ms2]]
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[[Category: Escherichia phage MS2]]
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[[Category: Grahn, E]]
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[[Category: Large Structures]]
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[[Category: Liljas, L]]
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[[Category: Grahn E]]
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[[Category: Stonehouse, N J]]
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[[Category: Liljas L]]
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[[Category: Valegard, K]]
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[[Category: Stonehouse NJ]]
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[[Category: Vandenworm, S]]
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[[Category: Valegard K]]
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[[Category: Coat protein]]
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[[Category: Vandenworm S]]
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[[Category: Icosahedral virus]]
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[[Category: Rna fragment]]
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[[Category: Rna-binding]]
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[[Category: Viral protein capsid]]
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[[Category: Virus-rna complex]]
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Current revision

STRUCTURE OF BACTERIOPHAGE COAT PROTEIN-LOOP RNA COMPLEX

PDB ID 1zdk

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