1y6j

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==L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135==
==L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135==
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<StructureSection load='1y6j' size='340' side='right' caption='[[1y6j]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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<StructureSection load='1y6j' size='340' side='right'caption='[[1y6j]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1y6j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27405 Atcc 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y6J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1y6j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y6J FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cth-1135 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1515 ATCC 27405])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y6j OCA], [https://pdbe.org/1y6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y6j RCSB], [https://www.ebi.ac.uk/pdbsum/1y6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y6j ProSAT], [https://www.topsan.org/Proteins/SECSG/1y6j TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y6j OCA], [http://pdbe.org/1y6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y6j RCSB], [http://www.ebi.ac.uk/pdbsum/1y6j PDBsum], [http://www.topsan.org/Proteins/SECSG/1y6j TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A3DCA4_ACET2 A3DCA4_ACET2] Catalyzes the conversion of lactate to pyruvate.[HAMAP-Rule:MF_00488]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y6/1y6j_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y6/1y6j_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y6j ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 27405]]
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[[Category: Acetivibrio thermocellus]]
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[[Category: L-lactate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Chen, L R]]
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[[Category: Chen LR]]
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[[Category: Habel, J]]
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[[Category: Habel J]]
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[[Category: Kataeva, I]]
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[[Category: Kataeva I]]
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[[Category: Lee, D]]
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[[Category: Lee D]]
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[[Category: Lin, D]]
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[[Category: Lin D]]
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[[Category: Liu, Z J]]
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[[Category: Liu Z-J]]
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[[Category: Ljungdahl, L]]
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[[Category: Ljungdahl L]]
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[[Category: Rose, J]]
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[[Category: Rose J]]
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[[Category: Structural genomic]]
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[[Category: Tempel W]]
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[[Category: Tempel, W]]
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[[Category: Wang B-C]]
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[[Category: Wang, B C]]
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[[Category: Yang H]]
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[[Category: Yang, H]]
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[[Category: Zhou W]]
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[[Category: Zhou, W]]
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[[Category: Clostridium thermocellum]]
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[[Category: Oxidoreductase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Secsg]]
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Current revision

L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135

PDB ID 1y6j

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