2o08

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[[Image:2o08.gif|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF A PUTATIVE HD SUPERFAMILY HYDROLASE (BH1327) FROM BACILLUS HALODURANS AT 1.90 A RESOLUTION==
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|PDB= 2o08 |SIZE=350|CAPTION= <scene name='initialview01'>2o08</scene>, resolution 1.900&Aring;
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<StructureSection load='2o08' size='340' side='right'caption='[[2o08]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=DGI:2&#39;-DEOXYGUANOSINE-5&#39;-DIPHOSPHATE'>DGI</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>
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<table><tr><td colspan='2'>[[2o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O08 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= NP_242193.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 Bacillus halodurans])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGI:2-DEOXYGUANOSINE-5-DIPHOSPHATE'>DGI</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00077 HDc]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o08 OCA], [https://pdbe.org/2o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o08 RCSB], [https://www.ebi.ac.uk/pdbsum/2o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o08 ProSAT], [https://www.topsan.org/Proteins/JCSG/2o08 TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o08 OCA], [http://www.ebi.ac.uk/pdbsum/2o08 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2o08 RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/AP4AH_HALH5 AP4AH_HALH5] Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield ADP.[UniProtKB:Q2G297]
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'''Crystal structure of a putative HD superfamily hydrolase (NP_242193.1) from Bacillus halodurans at 1.90 A resolution'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2O08 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O08 OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o0/2o08_consurf.spt"</scriptWhenChecked>
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[[Category: Bacillus halodurans]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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</jmolCheckbox>
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[[Category: hypothetical protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o08 ConSurf].
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[[Category: jcsg]]
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<div style="clear:both"></div>
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[[Category: joint center for structural genomic]]
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__TOC__
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[[Category: np_242193 1]]
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</StructureSection>
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[[Category: protein structure initiative]]
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[[Category: Alkalihalobacillus halodurans]]
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[[Category: psi-2]]
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[[Category: Large Structures]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 25 23:32:03 2008''
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Current revision

CRYSTAL STRUCTURE OF A PUTATIVE HD SUPERFAMILY HYDROLASE (BH1327) FROM BACILLUS HALODURANS AT 1.90 A RESOLUTION

PDB ID 2o08

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