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1t2t
From Proteopedia
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==Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site== | ==Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site== | ||
| - | <StructureSection load='1t2t' size='340' side='right' caption='[[1t2t]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='1t2t' size='340' side='right'caption='[[1t2t]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1t2t]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1t2t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T2T FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t2t OCA], [https://pdbe.org/1t2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t2t RCSB], [https://www.ebi.ac.uk/pdbsum/1t2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t2t ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TEV1_BPT4 TEV1_BPT4] This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t2/1t2t_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t2/1t2t_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t2t ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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==See Also== | ==See Also== | ||
| - | *[[Endonuclease|Endonuclease]] | + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia virus T4]] |
| - | [[Category: Belfort | + | [[Category: Large Structures]] |
| - | [[Category: Boyd | + | [[Category: Belfort M]] |
| - | [[Category: Derbyshire | + | [[Category: Boyd TM]] |
| - | [[Category: Edgell | + | [[Category: Derbyshire V]] |
| - | [[Category: LaBonne | + | [[Category: Edgell DR]] |
| - | [[Category: Li | + | [[Category: LaBonne S]] |
| - | + | [[Category: Li Z]] | |
| - | [[Category: Shub | + | [[Category: Shub DA]] |
| - | [[Category: Stanger | + | [[Category: Stanger MJ]] |
| - | [[Category: | + | [[Category: Van Roey P]] |
| - | + | ||
Current revision
Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site
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Categories: Escherichia virus T4 | Large Structures | Belfort M | Boyd TM | Derbyshire V | Edgell DR | LaBonne S | Li Z | Shub DA | Stanger MJ | Van Roey P
