2k3k

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==Solution structure of Drosophila melanogaster SNF RBD1==
==Solution structure of Drosophila melanogaster SNF RBD1==
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<StructureSection load='2k3k' size='340' side='right' caption='[[2k3k]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2k3k' size='340' side='right'caption='[[2k3k]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K3K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2k3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fjj 2fjj]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K3K FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [http://pdbe.org/2k3k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [http://www.ebi.ac.uk/pdbsum/2k3k PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3k OCA], [https://pdbe.org/2k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k3k RCSB], [https://www.ebi.ac.uk/pdbsum/2k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k3k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SNRPA_DROME SNRPA_DROME]] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing.
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[https://www.uniprot.org/uniprot/SNRPA_DROME SNRPA_DROME] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k3/2k3k_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k3/2k3k_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k3k ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Nucleoprotein|Nucleoprotein]]
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*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Cui, G]]
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[[Category: Large Structures]]
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[[Category: Hu, J]]
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[[Category: Cui G]]
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[[Category: Jin, C]]
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[[Category: Hu J]]
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[[Category: Liu, C]]
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[[Category: Jin C]]
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[[Category: Xia, B]]
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[[Category: Liu C]]
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[[Category: Mrna processing]]
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[[Category: Xia B]]
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[[Category: Mrna splicing]]
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[[Category: Nucleus]]
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[[Category: Ribonucleoprotein]]
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[[Category: Rna binding]]
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[[Category: Rna binding protein]]
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[[Category: Rna splicing]]
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[[Category: Rna-binding]]
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[[Category: Snf rbd1]]
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[[Category: Solution structure]]
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[[Category: Spliceosome]]
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Current revision

Solution structure of Drosophila melanogaster SNF RBD1

PDB ID 2k3k

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