2dtn

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==Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate==
==Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate==
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<StructureSection load='2dtn' size='340' side='right' caption='[[2dtn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2dtn' size='340' side='right'caption='[[2dtn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dtn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DTN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dtn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d2r|2d2r]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ditrans,polycis-undecaprenyl-diphosphate_synthase_((2E,6E)-farnesyl-_diphosphate_specific) Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl- diphosphate specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtn OCA], [https://pdbe.org/2dtn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dtn RCSB], [https://www.ebi.ac.uk/pdbsum/2dtn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dtn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtn OCA], [http://pdbe.org/2dtn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dtn RCSB], [http://www.ebi.ac.uk/pdbsum/2dtn PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ISPT_HELPY ISPT_HELPY]] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
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[https://www.uniprot.org/uniprot/ISPT_HELPY ISPT_HELPY] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dtn_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dtn_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dtn ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43504]]
 
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[[Category: Chen, C L]]
 
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[[Category: Guo, R T]]
 
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[[Category: Ko, T P]]
 
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[[Category: Kuo, C J]]
 
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[[Category: Liang, P H]]
 
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[[Category: Wang, A H.J]]
 
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[[Category: Cis prenyltransferase]]
 
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Transferase]]
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[[Category: Large Structures]]
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[[Category: Chen CL]]
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[[Category: Guo RT]]
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[[Category: Ko TP]]
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[[Category: Kuo CJ]]
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[[Category: Liang PH]]
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[[Category: Wang AH-J]]

Current revision

Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate

PDB ID 2dtn

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