2i9u

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==Crystal Structure of Guanine Deaminase from C. acetobutylicum with bound guanine in the active site==
==Crystal Structure of Guanine Deaminase from C. acetobutylicum with bound guanine in the active site==
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<StructureSection load='2i9u' size='340' side='right' caption='[[2i9u]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='2i9u' size='340' side='right'caption='[[2i9u]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2i9u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cloab Cloab]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I9U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2i9u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_acetobutylicum_ATCC_824 Clostridium acetobutylicum ATCC 824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I9U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GUN:GUANINE'>GUN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GUN:GUANINE'>GUN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i9u OCA], [http://pdbe.org/2i9u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i9u RCSB], [http://www.ebi.ac.uk/pdbsum/2i9u PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2i9u TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i9u OCA], [https://pdbe.org/2i9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i9u RCSB], [https://www.ebi.ac.uk/pdbsum/2i9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i9u ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2i9u TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q97MB6_CLOAB Q97MB6_CLOAB]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i9/2i9u_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i9/2i9u_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i9u ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Deaminase|Deaminase]]
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*[[Deaminase 3D structures|Deaminase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cloab]]
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[[Category: Clostridium acetobutylicum ATCC 824]]
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[[Category: Guanine deaminase]]
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[[Category: Large Structures]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Kumaran, D]]
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[[Category: Kumaran D]]
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[[Category: Structural genomic]]
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[[Category: Swaminathan S]]
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[[Category: Swaminathan, S]]
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[[Category: Amidohydrolase]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide transport and metabolism]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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Current revision

Crystal Structure of Guanine Deaminase from C. acetobutylicum with bound guanine in the active site

PDB ID 2i9u

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