2os0
From Proteopedia
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==Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes== | ==Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes== | ||
- | <StructureSection load='2os0' size='340' side='right' caption='[[2os0]], [[Resolution|resolution]] 1.30Å' scene=''> | + | <StructureSection load='2os0' size='340' side='right'caption='[[2os0]], [[Resolution|resolution]] 1.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2os0]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2os0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OS0 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2os0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2os0 OCA], [https://pdbe.org/2os0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2os0 RCSB], [https://www.ebi.ac.uk/pdbsum/2os0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2os0 ProSAT]</span></td></tr> |
- | + | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/DEF_ENTFA DEF_ENTFA] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2os0_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2os0_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2os0 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Enterococcus | + | [[Category: Enterococcus faecalis]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Choi | + | [[Category: Choi K]] |
- | [[Category: Kim | + | [[Category: Kim EE]] |
- | [[Category: Kim | + | [[Category: Kim K-H]] |
- | [[Category: Lee | + | [[Category: Lee HK]] |
- | [[Category: Moon | + | [[Category: Moon JH]] |
- | [[Category: Park | + | [[Category: Park HS]] |
- | + | ||
- | + |
Current revision
Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes
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Categories: Enterococcus faecalis | Large Structures | Choi K | Kim EE | Kim K-H | Lee HK | Moon JH | Park HS