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1lvw

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[[Image:1lvw.gif|left|200px]]
 
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{{Structure
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==Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP==
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|PDB= 1lvw |SIZE=350|CAPTION= <scene name='initialview01'>1lvw</scene>, resolution 1.7&Aring;
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<StructureSection load='1lvw' size='340' side='right'caption='[[1lvw]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYD:THYMIDINE-5&#39;-+DIPHOSPHATE'>TYD</scene>
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<table><tr><td colspan='2'>[[1lvw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LVW FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_thymidylyltransferase Glucose-1-phosphate thymidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.24 2.7.7.24] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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|GENE= RMLA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 Methanothermobacter thermautotrophicus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00483 NTP_transferase], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1209 RfbA]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lvw OCA], [https://pdbe.org/1lvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lvw RCSB], [https://www.ebi.ac.uk/pdbsum/1lvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lvw ProSAT], [https://www.topsan.org/Proteins/NESGC/1lvw TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lvw OCA], [http://www.ebi.ac.uk/pdbsum/1lvw PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1lvw RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/O27819_METTH O27819_METTH]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lvw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lvw ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP'''
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==See Also==
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*[[Glucose-1-phosphate thymidylyltransferase 3D structures|Glucose-1-phosphate thymidylyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1LVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVW OCA].
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[[Category: Large Structures]]
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[[Category: Glucose-1-phosphate thymidylyltransferase]]
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[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Single protein]]
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[[Category: Christendat D]]
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[[Category: Christendat, D.]]
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[[Category: Dong A]]
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[[Category: Dong, A.]]
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[[Category: Pai EF]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Pai, E F.]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: nucleotide binding fold]]
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[[Category: protein nucleotide complex]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 05:56:19 2008''
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Current revision

Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP

PDB ID 1lvw

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