1h9v

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==HUMAN FC-GAMMA-RECEPTOR IIA (FCGRIIA), MONOCLINIC==
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<StructureSection load='1h9v' size='340' side='right' caption='[[1h9v]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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==Human Fc-gamma-Receptor IIa (FcgRIIa), monoclinic==
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<StructureSection load='1h9v' size='340' side='right'caption='[[1h9v]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1h9v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H9V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1h9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H9V FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fcg|1fcg]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h9v OCA], [http://pdbe.org/1h9v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h9v RCSB], [http://www.ebi.ac.uk/pdbsum/1h9v PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h9v OCA], [https://pdbe.org/1h9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h9v RCSB], [https://www.ebi.ac.uk/pdbsum/1h9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h9v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FCG2A_HUMAN FCG2A_HUMAN]] Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.<ref>PMID:19011614</ref>
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[https://www.uniprot.org/uniprot/FCG2A_HUMAN FCG2A_HUMAN] Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.<ref>PMID:19011614</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/1h9v_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/1h9v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h9v ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Jacob, U]]
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[[Category: Large Structures]]
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[[Category: Kaiser, J]]
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[[Category: Jacob U]]
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[[Category: Sondermann, P]]
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[[Category: Kaiser J]]
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[[Category: Fc-gamma-r]]
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[[Category: Sondermann P]]
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[[Category: Fc-receptor]]
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[[Category: Fcgr]]
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[[Category: Fcr]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin]]
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[[Category: Membrane protein]]
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Current revision

Human Fc-gamma-Receptor IIa (FcgRIIa), monoclinic

PDB ID 1h9v

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