1p9k

<StructureSection load='1p9k' size='340' side='right' caption='[[1p9k]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[1p9k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1o09 1o09]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P9K FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ybcJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p9k OCA], [http://pdbe.org/1p9k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p9k RCSB], [http://www.ebi.ac.uk/pdbsum/1p9k PDBsum], [http://www.topsan.org/Proteins/BSGI/1p9k TOPSAN]</span></td></tr>

[[http://www.uniprot.org/uniprot/YBCJ_ECOLI YBCJ_ECOLI]] Its structure and the presence of conserved basic residues indicates that it probably binds RNA.

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p9/1p9k_consurf.spt"</scriptWhenChecked>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

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== Publication Abstract from PubMed ==

The structure of the recombinant Escherichia coli protein YbcJ, a representative of a conserved family of bacterial proteins (COG2501), was determined by nuclear magnetic resonance. The fold of YbcJ identified it as a member of the larger family of S4-like RNA binding domains. These domains bind to structured RNA, such as that found in tRNA, rRNA, and a pseudoknot of mRNA. The structure of YbcJ revealed a highly conserved patch of basic residues, comprising amino acids K26, K38, R55, K56, and K59, which likely participate in RNA binding.

The solution structure of YbcJ from Escherichia coli reveals a recently discovered alphaL motif involved in RNA binding.,Volpon L, Lievre C, Osborne MJ, Gandhi S, Iannuzzi P, Larocque R, Cygler M, Gehring K, Ekiel I J Bacteriol. 2003 Jul;185(14):4204-10. PMID:12837795<ref>PMID:12837795</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

</div>

<div class="pdbe-citations 1p9k" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Ecoli]]

[[Category: Structural genomic]]

[[Category: Cygler, M]]

[[Category: Ekiel, I]]

[[Category: Gandhi, S]]

[[Category: Gehring, K]]

[[Category: Iannuzzi, P]]

[[Category: Larocque, R]]

[[Category: Lievre, C]]

[[Category: Matte, A]]

[[Category: Osborne, M J]]

[[Category: Volpon, L]]

[[Category: Rna-binding protein]]