This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1pm3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:09, 14 February 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1pm3.gif|left|200px]]
 
-
{{Structure
+
==MTH1859==
-
|PDB= 1pm3 |SIZE=350|CAPTION= <scene name='initialview01'>1pm3</scene>, resolution 3.15&Aring;
+
<StructureSection load='1pm3' size='340' side='right'caption='[[1pm3]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1pm3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PM3 FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
-
|GENE=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pm3 OCA], [https://pdbe.org/1pm3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pm3 RCSB], [https://www.ebi.ac.uk/pdbsum/1pm3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pm3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1pm3 TOPSAN]</span></td></tr>
-
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1873 COG1873]</span>
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pm3 OCA], [http://www.ebi.ac.uk/pdbsum/1pm3 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1pm3 RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/O27887_METTH O27887_METTH]
-
 
+
__TOC__
-
'''MTH1859'''
+
</StructureSection>
-
 
+
[[Category: Large Structures]]
-
 
+
-
==Overview==
+
-
MTH1859 from Methanobacterium thermoautotrophicum is a 77 residue protein representing a conserved family of functionally uncharacterized proteins. We solved the crystal structure of MTH1859 by single wavelength anomalous diffraction phasing using selenomethionine labeled protein. MTH1859 adopts a mainly anti-parallel all-beta-fold. The beta-sheet is heavily bent to form a U-structure that is closed through a loop. The monomer structure possesses similarities to the photoreaction center (PRC) domain fold, but the protein employs a unique oligomerization scheme. Two monomers of MTH1859 occupy the asymmetric unit and dimerize in a head-to-head fashion. Crystal packing interactions identify a second protein-protein interaction interface at the MTH1859 tails which can simultaneously bind two partner molecules. These interactions lead to the formation of a honeycomb structure and suggest that the family of MTH1859-like proteins might function as adapters for protein complex assembly.
+
-
 
+
-
==About this Structure==
+
-
1PM3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PM3 OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of the putative adapter protein MTH1859., Ye H, Chen TC, Xu X, Pennycooke M, Wu H, Steegborn C, J Struct Biol. 2004 Nov;148(2):251-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15477104 15477104]
+
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
-
[[Category: Single protein]]
+
[[Category: Steegborn C]]
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
[[Category: Wu H]]
-
[[Category: Steegborn, C.]]
+
[[Category: Ye H]]
-
[[Category: Wu, H.]]
+
-
[[Category: Ye, H.]]
+
-
[[Category: nesg]]
+
-
[[Category: northeast structural genomics consortium]]
+
-
[[Category: protein structure initiative]]
+
-
[[Category: psi]]
+
-
[[Category: structural genomic]]
+
-
[[Category: unknown function]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:00:42 2008''
+

Current revision

MTH1859

PDB ID 1pm3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pm3"
Personal tools