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2l5f
From Proteopedia
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==Solution structure of the tandem WW domains from HYPA/FBP11== | ==Solution structure of the tandem WW domains from HYPA/FBP11== | ||
| - | <StructureSection load='2l5f' size='340' side='right' caption='[[2l5f | + | <StructureSection load='2l5f' size='340' side='right'caption='[[2l5f]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2l5f]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2l5f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L5F FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l5f OCA], [https://pdbe.org/2l5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l5f RCSB], [https://www.ebi.ac.uk/pdbsum/2l5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l5f ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hu H]] |
| - | [[Category: | + | [[Category: Jiang Y]] |
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Current revision
Solution structure of the tandem WW domains from HYPA/FBP11
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