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1yrv

From Proteopedia

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==Novel Ubiquitin-Conjugating Enzyme==
==Novel Ubiquitin-Conjugating Enzyme==
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<StructureSection load='1yrv' size='340' side='right' caption='[[1yrv]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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<StructureSection load='1yrv' size='340' side='right'caption='[[1yrv]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1yrv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YRV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YRV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1yrv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YRV FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MGC35130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yrv OCA], [https://pdbe.org/1yrv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yrv RCSB], [https://www.ebi.ac.uk/pdbsum/1yrv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yrv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yrv OCA], [http://pdbe.org/1yrv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yrv RCSB], [http://www.ebi.ac.uk/pdbsum/1yrv PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UBE2U_HUMAN UBE2U_HUMAN]] Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
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[https://www.uniprot.org/uniprot/UBE2U_HUMAN UBE2U_HUMAN] Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yr/1yrv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yr/1yrv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yrv ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Ubiquitin--protein ligase]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C]]
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[[Category: Arrowsmith C]]
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[[Category: Avvakumov, G V]]
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[[Category: Avvakumov GV]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Choe, J]]
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[[Category: Choe J]]
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[[Category: Dhe-Paganon, S]]
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[[Category: Dhe-Paganon S]]
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[[Category: Edwards, A]]
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[[Category: Edwards A]]
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[[Category: MacKenzie, F]]
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[[Category: MacKenzie F]]
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[[Category: Newman, E M]]
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[[Category: Newman EM]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M]]
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[[Category: Walker JR]]
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[[Category: Walker, J R]]
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[[Category: Ligase]]
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[[Category: Sgc]]
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[[Category: Ubiquitin]]
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[[Category: Ubiquitin-conjugating enzyme]]
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Current revision

Novel Ubiquitin-Conjugating Enzyme

PDB ID 1yrv

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