2iw1

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==CRYSTAL STRUCTURE OF WAAG, A GLYCOSYLTRANSFERASE INVOLVED IN LIPOPOLYSACCHARIDE BIOSYNTHESIS==
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<StructureSection load='2iw1' size='340' side='right' caption='[[2iw1]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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==Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis==
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<StructureSection load='2iw1' size='340' side='right'caption='[[2iw1]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecow3 Ecow3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IW1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2iw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._W3110 Escherichia coli str. K-12 substr. W3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IW1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U2F:URIDINE-5-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE'>U2F</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iv7|2iv7]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U2F:URIDINE-5-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE'>U2F</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iw1 OCA], [http://pdbe.org/2iw1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2iw1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iw1 OCA], [https://pdbe.org/2iw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iw1 RCSB], [https://www.ebi.ac.uk/pdbsum/2iw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iw1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RFAG_ECOLI RFAG_ECOLI]] Involved in the addition of the first glucose residue to the lipopolysaccharide core.
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[https://www.uniprot.org/uniprot/RFAG_ECOLI RFAG_ECOLI] Involved in the addition of the first glucose residue to the lipopolysaccharide core.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iw1_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iw1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iw1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Glycosyltransferase|Glycosyltransferase]]
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecow3]]
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[[Category: Escherichia coli str. K-12 substr. W3110]]
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[[Category: Bolam, D N]]
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[[Category: Large Structures]]
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[[Category: Davies, G J]]
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[[Category: Bolam DN]]
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[[Category: Gilbert, H J]]
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[[Category: Davies GJ]]
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[[Category: Martinez-Fleites, C]]
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[[Category: Gilbert HJ]]
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[[Category: Proctor, M]]
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[[Category: Martinez-Fleites C]]
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[[Category: Roberts, S]]
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[[Category: Proctor M]]
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[[Category: Family gt-4]]
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[[Category: Roberts S]]
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[[Category: Glycosyltransferase]]
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[[Category: Lipopolysaccharide biosynthesis]]
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[[Category: Lp]]
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[[Category: Retaining]]
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[[Category: Transferase]]
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[[Category: Udp-glucose]]
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Current revision

Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis

PDB ID 2iw1

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