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1jq0

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==Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure.==
==Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure.==
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<StructureSection load='1jq0' size='340' side='right' caption='[[1jq0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1jq0' size='340' side='right'caption='[[1jq0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1jq0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Civ Civ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1jq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Simian_immunodeficiency_virus Simian immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQ0 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qbz|1qbz]], [[1jpx|1jpx]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jq0 OCA], [http://pdbe.org/1jq0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jq0 RCSB], [http://www.ebi.ac.uk/pdbsum/1jq0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jq0 OCA], [https://pdbe.org/1jq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jq0 RCSB], [https://www.ebi.ac.uk/pdbsum/1jq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jq0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S4WCF9_SIV S4WCF9_SIV]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jq0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jq0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jq0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Gp41|Gp41]]
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*[[Gp41 3D Structures|Gp41 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Civ]]
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[[Category: Large Structures]]
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[[Category: Hoxie, J A]]
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[[Category: Simian immunodeficiency virus]]
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[[Category: LaBranche, C C]]
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[[Category: Hoxie JA]]
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[[Category: Liu, J]]
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[[Category: LaBranche CC]]
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[[Category: Lu, M]]
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[[Category: Liu J]]
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[[Category: Wang, S]]
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[[Category: Lu M]]
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[[Category: Gp41]]
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[[Category: Wang S]]
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[[Category: Hiv-1]]
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[[Category: Membrane fusion]]
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[[Category: Siv]]
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[[Category: Six-helix bundle]]
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[[Category: Trimer-of-hairpin]]
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[[Category: Viral protein]]
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Current revision

Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure.

PDB ID 1jq0

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