2o3j

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==Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase==
==Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase==
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<StructureSection load='2o3j' size='340' side='right' caption='[[2o3j]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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<StructureSection load='2o3j' size='340' side='right'caption='[[2o3j]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2o3j]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O3J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2o3j]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O3J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_6-dehydrogenase UDP-glucose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.22 1.1.1.22] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o3j OCA], [http://pdbe.org/2o3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o3j RCSB], [http://www.ebi.ac.uk/pdbsum/2o3j PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2o3j TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o3j OCA], [https://pdbe.org/2o3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o3j RCSB], [https://www.ebi.ac.uk/pdbsum/2o3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o3j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2o3j TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UGDH_CAEEL UGDH_CAEEL]] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
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[https://www.uniprot.org/uniprot/UGDH_CAEEL UGDH_CAEEL] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o3/2o3j_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o3/2o3j_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o3j ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caeel]]
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[[Category: Caenorhabditis elegans]]
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[[Category: UDP-glucose 6-dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Milst, S]]
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[[Category: Milst S]]
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[[Category: Structural genomic]]
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[[Category: Patskovsky Y]]
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[[Category: Patskovsky, Y]]
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[[Category: Ramagopal U]]
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[[Category: Ramagopal, U]]
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[[Category: Shi W]]
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[[Category: Shi, W]]
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[[Category: Toro R]]
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[[Category: Toro, R]]
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[[Category: Vidal M]]
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[[Category: Vidal, M]]
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[[Category: Wengerter BC]]
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[[Category: Wengerter, B C]]
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[[Category: Zhan C]]
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[[Category: Zhan, C]]
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[[Category: Zhang Y]]
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[[Category: Zhang, Y]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: Oxidoreductase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Udp-glucose dehydrogenase]]
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Current revision

Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase

PDB ID 2o3j

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