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1h9h

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==COMPLEX OF EETI-II WITH PORCINE TRYPSIN==
==COMPLEX OF EETI-II WITH PORCINE TRYPSIN==
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<StructureSection load='1h9h' size='340' side='right' caption='[[1h9h]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='1h9h' size='340' side='right'caption='[[1h9h]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1h9h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H9H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1h9h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecballium_elaterium Ecballium elaterium] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H9H FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aks|1aks]], [[1an1|1an1]], [[1avw|1avw]], [[1avx|1avx]], [[1c9p|1c9p]], [[1d3o|1d3o]], [[1df2|1df2]], [[1eja|1eja]], [[1ept|1ept]], [[1ewu|1ewu]], [[1fmg|1fmg]], [[1fn6|1fn6]], [[1fni|1fni]], [[1ldt|1ldt]], [[1lt2|1lt2]], [[1mct|1mct]], [[1qqu|1qqu]], [[1r0t|1r0t]], [[1s5s|1s5s]], [[1s6f|1s6f]], [[1s6h|1s6h]], [[1s81|1s81]], [[1s82|1s82]], [[1s83|1s83]], [[1s84|1s84]], [[1s85|1s85]], [[1tfx|1tfx]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h9h OCA], [https://pdbe.org/1h9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h9h RCSB], [https://www.ebi.ac.uk/pdbsum/1h9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h9h ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h9h OCA], [http://pdbe.org/1h9h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h9h RCSB], [http://www.ebi.ac.uk/pdbsum/1h9h PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ITR2_ECBEL ITR2_ECBEL]] Inhibits trypsin.
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[https://www.uniprot.org/uniprot/TRYP_PIG TRYP_PIG]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/1h9h_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/1h9h_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h9h ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Trypsin|Trypsin]]
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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*[[Trypsin inhibitor|Trypsin inhibitor]]
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*[[Trypsin inhibitor 3D structures|Trypsin inhibitor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecballium elaterium]]
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Trypsin]]
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[[Category: Kolmar H]]
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[[Category: Kolmar, H]]
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[[Category: Kraetzner R]]
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[[Category: Kraetzner, R]]
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[[Category: Uson I]]
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[[Category: Uson, I]]
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[[Category: Wentzel A]]
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[[Category: Wentzel, A]]
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[[Category: Cystine knot]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Squash inhibitor]]
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Current revision

COMPLEX OF EETI-II WITH PORCINE TRYPSIN

PDB ID 1h9h

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