This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2cot

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:27, 22 May 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Solution structure of the first and second zf-C2H2 domain of Zinc finger protein 435==
==Solution structure of the first and second zf-C2H2 domain of Zinc finger protein 435==
-
<StructureSection load='2cot' size='340' side='right' caption='[[2cot]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2cot' size='340' side='right'caption='[[2cot]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2cot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2COT FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2cot]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COT FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF435, ZSCAN16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cot OCA], [http://pdbe.org/2cot PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cot RCSB], [http://www.ebi.ac.uk/pdbsum/2cot PDBsum], [http://www.topsan.org/Proteins/RSGI/2cot TOPSAN]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cot OCA], [https://pdbe.org/2cot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cot RCSB], [https://www.ebi.ac.uk/pdbsum/2cot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cot ProSAT], [https://www.topsan.org/Proteins/RSGI/2cot TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ZSC16_HUMAN ZSC16_HUMAN]] May be involved in transcriptional regulation.
+
[https://www.uniprot.org/uniprot/ZSC16_HUMAN ZSC16_HUMAN] May be involved in transcriptional regulation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/2cot_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/2cot_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cot ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Hayashi, F]]
+
[[Category: Large Structures]]
-
[[Category: Nagashima, T]]
+
[[Category: Hayashi F]]
-
[[Category: Qin, X R]]
+
[[Category: Nagashima T]]
-
[[Category: Structural genomic]]
+
[[Category: Qin XR]]
-
[[Category: Yokoyama, S]]
+
[[Category: Yokoyama S]]
-
[[Category: Adk_lid domain]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Transcription]]
+
-
[[Category: Zinc finger and scan domain containing protein 16]]
+
-
[[Category: Zinc finger protein 435]]
+

Current revision

Solution structure of the first and second zf-C2H2 domain of Zinc finger protein 435

PDB ID 2cot

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools