2dfj
From Proteopedia
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==Crystal Structure of the Diadenosine Tetraphosphate Hydrolase from Shigella flexneri 2a== | ==Crystal Structure of the Diadenosine Tetraphosphate Hydrolase from Shigella flexneri 2a== | ||
| - | <StructureSection load='2dfj' size='340' side='right' caption='[[2dfj]], [[Resolution|resolution]] 2.72Å' scene=''> | + | <StructureSection load='2dfj' size='340' side='right'caption='[[2dfj]], [[Resolution|resolution]] 2.72Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dfj]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dfj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri_2a Shigella flexneri 2a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.72Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfj OCA], [https://pdbe.org/2dfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfj RCSB], [https://www.ebi.ac.uk/pdbsum/2dfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfj ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/APAH_SHIFL APAH_SHIFL] Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.[HAMAP-Rule:MF_00199] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfj_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfj_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dfj ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Shigella flexneri 2a]] | [[Category: Shigella flexneri 2a]] | ||
| - | [[Category: Bi | + | [[Category: Bi RC]] |
| - | [[Category: Hu | + | [[Category: Hu WX]] |
| - | [[Category: Wang | + | [[Category: Wang QH]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the Diadenosine Tetraphosphate Hydrolase from Shigella flexneri 2a
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