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1y0b

From Proteopedia

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[[Image:1y0b.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of Xanthine Phosphoribosyltransferase from Bacillus subtilis.==
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|PDB= 1y0b |SIZE=350|CAPTION= <scene name='initialview01'>1y0b</scene>, resolution 1.80&Aring;
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<StructureSection load='1y0b' size='340' side='right'caption='[[1y0b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=G4P:GUANOSINE-5&#39;,3&#39;-TETRAPHOSPHATE'>G4P</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
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<table><tr><td colspan='2'>[[1y0b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y0B FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= xpt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G4P:GUANOSINE-5,3-TETRAPHOSPHATE'>G4P</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK09219 PRK09219]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y0b OCA], [https://pdbe.org/1y0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y0b RCSB], [https://www.ebi.ac.uk/pdbsum/1y0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y0b ProSAT], [https://www.topsan.org/Proteins/MCSG/1y0b TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y0b OCA], [http://www.ebi.ac.uk/pdbsum/1y0b PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1y0b RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/XPT_BACSU XPT_BACSU] Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthesis.[HAMAP-Rule:MF_01184]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y0/1y0b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y0b ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of Xanthine Phosphoribosyltransferase from Bacillus subtilis.'''
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1Y0B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y0B OCA].
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Cuff, M E.]]
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[[Category: Cuff ME]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Wu R]]
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[[Category: Wu, R.]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: phosphoribosyltransferase]]
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[[Category: protein structure initative]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: purine metabolism]]
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[[Category: structural genomic]]
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[[Category: xanthine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:13:17 2008''
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Current revision

Crystal Structure of Xanthine Phosphoribosyltransferase from Bacillus subtilis.

PDB ID 1y0b

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