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1uuz

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==IVY:A NEW FAMILY OF PROTEIN==
==IVY:A NEW FAMILY OF PROTEIN==
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<StructureSection load='1uuz' size='340' side='right' caption='[[1uuz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='1uuz' size='340' side='right'caption='[[1uuz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uuz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885] and [http://en.wikipedia.org/wiki/Chick Chick]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hke 1hke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UUZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uuz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hke 1hke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UUZ FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[132l|132l]], [[193l|193l]], [[194l|194l]], [[1a2y|1a2y]], [[1aki|1aki]], [[1at5|1at5]], [[1at6|1at6]], [[1azf|1azf]], [[1b0d|1b0d]], [[1b2k|1b2k]], [[1bgi|1bgi]], [[1bhz|1bhz]], [[1bvk|1bvk]], [[1bvx|1bvx]], [[1bwh|1bwh]], [[1bwi|1bwi]], [[1bwj|1bwj]], [[1c08|1c08]], [[1c10|1c10]], [[1dpw|1dpw]], [[1dpx|1dpx]], [[1dqj|1dqj]], [[1e8l|1e8l]], [[1f0w|1f0w]], [[1f10|1f10]], [[1f3j|1f3j]], [[1fdl|1fdl]], [[1flq|1flq]], [[1flu|1flu]], [[1flw|1flw]], [[1fly|1fly]], [[1fn5|1fn5]], [[1g7h|1g7h]], [[1g7i|1g7i]], [[1g7j|1g7j]], [[1g7l|1g7l]], [[1g7m|1g7m]], [[1gpq|1gpq]], [[1gwd|1gwd]], [[1gxv|1gxv]], [[1gxx|1gxx]], [[1h6m|1h6m]], [[1h87|1h87]], [[1hc0|1hc0]], [[1hel|1hel]], [[1hem|1hem]], [[1hen|1hen]], [[1heo|1heo]], [[1hep|1hep]], [[1heq|1heq]], [[1her|1her]], [[1hew|1hew]], [[1hf4|1hf4]], [[1hsw|1hsw]], [[1hsx|1hsx]], [[1ic4|1ic4]], [[1ic5|1ic5]], [[1ic7|1ic7]], [[1iee|1iee]], [[1io5|1io5]], [[1ioq|1ioq]], [[1ior|1ior]], [[1ios|1ios]], [[1iot|1iot]], [[1ir7|1ir7]], [[1ir8|1ir8]], [[1ir9|1ir9]], [[1j1o|1j1o]], [[1j1p|1j1p]], [[1j1x|1j1x]], [[1ja2|1ja2]], [[1ja4|1ja4]], [[1ja6|1ja6]], [[1ja7|1ja7]], [[1jis|1jis]], [[1jit|1jit]], [[1jiy|1jiy]], [[1jj0|1jj0]], [[1jj1|1jj1]], [[1jj3|1jj3]], [[1jpo|1jpo]], [[1jto|1jto]], [[1jtt|1jtt]], [[1kip|1kip]], [[1kiq|1kiq]], [[1kir|1kir]], [[1kxw|1kxw]], [[1kxx|1kxx]], [[1kxy|1kxy]], [[1lcn|1lcn]], [[1lj3|1lj3]], [[1lj4|1lj4]], [[1lje|1lje]], [[1ljf|1ljf]], [[1ljg|1ljg]], [[1ljh|1ljh]], [[1lji|1lji]], [[1ljj|1ljj]], [[1ljk|1ljk]], [[1lkr|1lkr]], [[1lks|1lks]], [[1lma|1lma]], [[1lpi|1lpi]], [[1lsa|1lsa]], [[1lsb|1lsb]], [[1lsc|1lsc]], [[1lsd|1lsd]], [[1lse|1lse]], [[1lsf|1lsf]], [[1lsg|1lsg]], [[1lsm|1lsm]], [[1lsn|1lsn]], [[1lsy|1lsy]], [[1lsz|1lsz]], [[1lyo|1lyo]], [[1lys|1lys]], [[1lyz|1lyz]], [[1lz8|1lz8]], [[1lz9|1lz9]], [[1lza|1lza]], [[1lzb|1lzb]], [[1lzc|1lzc]], [[1lzd|1lzd]], [[1lze|1lze]], [[1lzg|1lzg]], [[1lzh|1lzh]], [[1lzn|1lzn]], [[1lzt|1lzt]], [[1mel|1mel]], [[1mlc|1mlc]], [[1n4f|1n4f]], [[1nby|1nby]], [[1nbz|1nbz]], [[1ndg|1ndg]], [[1ndm|1ndm]], [[1ps5|1ps5]], [[1qio|1qio]], [[1qtk|1qtk]], [[1rcm|1rcm]], [[1rfp|1rfp]], [[1uc0|1uc0]], [[1uco|1uco]], [[1uia|1uia]], [[1uib|1uib]], [[1uic|1uic]], [[1uid|1uid]], [[1uie|1uie]], [[1uif|1uif]], [[1uig|1uig]], [[1uih|1uih]], [[1vfb|1vfb]], [[1xei|1xei]], [[1xej|1xej]], [[1xek|1xek]], [[2cds|2cds]], [[2hfm|2hfm]], [[2iff|2iff]], [[2lym|2lym]], [[2lyo|2lyo]], [[2lyz|2lyz]], [[2lzh|2lzh]], [[2lzt|2lzt]], [[3hfl|3hfl]], [[3hfm|3hfm]], [[3lym|3lym]], [[3lyo|3lyo]], [[3lyt|3lyt]], [[3lyz|3lyz]], [[3lzt|3lzt]], [[4lym|4lym]], [[4lyo|4lyo]], [[4lyt|4lyt]], [[4lyz|4lyz]], [[4lzt|4lzt]], [[5lym|5lym]], [[5lyt|5lyt]], [[5lyz|5lyz]], [[6lyt|6lyt]], [[6lyz|6lyz]], [[7lyz|7lyz]], [[8lyz|8lyz]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uuz OCA], [https://pdbe.org/1uuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uuz RCSB], [https://www.ebi.ac.uk/pdbsum/1uuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uuz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uuz OCA], [http://pdbe.org/1uuz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uuz RCSB], [http://www.ebi.ac.uk/pdbsum/1uuz PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IVY_PSEAE IVY_PSEAE]] Strong inhibitor of lysozyme C. [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/IVY_PSEAE IVY_PSEAE] Strong inhibitor of lysozyme C.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uu/1uuz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uu/1uuz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uuz ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Abergel, C]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Byrne, D]]
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[[Category: Abergel C]]
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[[Category: Claverie, J M]]
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[[Category: Byrne D]]
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[[Category: Lembo, F]]
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[[Category: Claverie JM]]
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[[Category: Maza, C]]
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[[Category: Lembo F]]
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[[Category: Glycosidase]]
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[[Category: Maza C]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-inhibitor complex]]
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[[Category: Hydrolase/inhibitor]]
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[[Category: Ivy]]
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[[Category: Lysozyme-inhibitor complex]]
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[[Category: Type-c lysozyme inhibitor]]
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Current revision

IVY:A NEW FAMILY OF PROTEIN

PDB ID 1uuz

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