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2iik

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==Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)==
==Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)==
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<StructureSection load='2iik' size='340' side='right' caption='[[2iik]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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<StructureSection load='2iik' size='340' side='right'caption='[[2iik]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iik]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IIK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2iik]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IIK FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACAA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acyltransferase Acetyl-CoA C-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.16 2.3.1.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iik OCA], [https://pdbe.org/2iik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iik RCSB], [https://www.ebi.ac.uk/pdbsum/2iik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iik ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iik OCA], [http://pdbe.org/2iik PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iik RCSB], [http://www.ebi.ac.uk/pdbsum/2iik PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/THIK_HUMAN THIK_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iik_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iik_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iik ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Thiolase|Thiolase]]
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*[[Thiolase 3D structures|Thiolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetyl-CoA C-acyltransferase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F von]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, O]]
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[[Category: Gorrec F]]
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[[Category: Gorrec, F]]
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[[Category: Johansson C]]
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[[Category: Johansson, C]]
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[[Category: Kavanagh K]]
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[[Category: Kavanagh, K]]
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[[Category: Oppermann U]]
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[[Category: Oppermann, U]]
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[[Category: Papagrigoriou E]]
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[[Category: Papagrigoriou, E]]
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[[Category: Pike ACW]]
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[[Category: Pike, A C.W]]
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[[Category: Smee C]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom M]]
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[[Category: Smee, C]]
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[[Category: Umeano C]]
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[[Category: Sundstrom, M]]
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[[Category: Weigelt J]]
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[[Category: Umeano, C]]
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[[Category: Von Delft F]]
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[[Category: Weigelt, J]]
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[[Category: Fatty acid metabolism]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)

PDB ID 2iik

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