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1ywk

From Proteopedia

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[[Image:1ywk.gif|left|200px]]
 
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{{Structure
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==Crystal structure of 4-deoxy-1-threo-5-hexosulose-uronate ketol-isomerase from Enterococcus faecalis==
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|PDB= 1ywk |SIZE=350|CAPTION= <scene name='initialview01'>1ywk</scene>, resolution 2.95&Aring;
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<StructureSection load='1ywk' size='340' side='right'caption='[[1ywk]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1ywk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YWK FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/4-deoxy-L-threo-5-hexosulose-uronate_ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.17 5.3.1.17] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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|GENE= kduI1, kduI-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 Enterococcus faecalis])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ywk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ywk OCA], [https://pdbe.org/1ywk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ywk RCSB], [https://www.ebi.ac.uk/pdbsum/1ywk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ywk ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1ywk TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00924 PRK00924]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ywk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ywk OCA], [http://www.ebi.ac.uk/pdbsum/1ywk PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1ywk RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/KDUI1_ENTFA KDUI1_ENTFA] Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity).
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== Evolutionary Conservation ==
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'''Crystal structure of 4-deoxy-1-threo-5-hexosulose-uronate ketol-isomerase from Enterococcus faecalis'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yw/1ywk_consurf.spt"</scriptWhenChecked>
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1YWK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YWK OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ywk ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Fedorov, A A.]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, E V.]]
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[[Category: Fedorov EV]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: ketol-isomerase]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc target t1814]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:16:26 2008''
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Current revision

Crystal structure of 4-deoxy-1-threo-5-hexosulose-uronate ketol-isomerase from Enterococcus faecalis

PDB ID 1ywk

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OCA

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