2a08
From Proteopedia
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==Structure of the yeast YHH6 SH3 domain==  | ==Structure of the yeast YHH6 SH3 domain==  | ||
| - | <StructureSection load='2a08' size='340' side='right' caption='[[2a08]], [[Resolution|resolution]] 1.54Å' scene=''>  | + | <StructureSection load='2a08' size='340' side='right'caption='[[2a08]], [[Resolution|resolution]] 1.54Å' scene=''>  | 
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[2a08]] is a 2 chain structure with sequence from [  | + | <table><tr><td colspan='2'>[[2a08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A08 FirstGlance]. <br>  | 
| - | </td></tr><tr id='  | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54Å</td></tr>  | 
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[  | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a08 OCA], [https://pdbe.org/2a08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a08 RCSB], [https://www.ebi.ac.uk/pdbsum/2a08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a08 ProSAT]</span></td></tr>  | 
</table>  | </table>  | ||
== Function ==  | == Function ==  | ||
| - | [  | + | [https://www.uniprot.org/uniprot/YSC84_YEAST YSC84_YEAST] Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with LSB5.<ref>PMID:12388763</ref>   | 
== Evolutionary Conservation ==  | == Evolutionary Conservation ==  | ||
[[Image:Consurf_key_small.gif|200px|right]]  | [[Image:Consurf_key_small.gif|200px|right]]  | ||
Check<jmol>  | Check<jmol>  | ||
  <jmolCheckbox>  |   <jmolCheckbox>  | ||
| - |     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/2a08_consurf.spt"</scriptWhenChecked>  | + |     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/2a08_consurf.spt"</scriptWhenChecked>  | 
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  |     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  | ||
    <text>to colour the structure by Evolutionary Conservation</text>  |     <text>to colour the structure by Evolutionary Conservation</text>  | ||
  </jmolCheckbox>  |   </jmolCheckbox>  | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/  | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a08 ConSurf].  | 
<div style="clear:both"></div>  | <div style="clear:both"></div>  | ||
== References ==  | == References ==  | ||
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__TOC__  | __TOC__  | ||
</StructureSection>  | </StructureSection>  | ||
| - | [[Category:   | + | [[Category: Large Structures]]  | 
| - | [[Category: Kursula  | + | [[Category: Saccharomyces cerevisiae]]  | 
| - | [[Category: Kursula  | + | [[Category: Kursula I]]  | 
| - | [[Category: Lehmann  | + | [[Category: Kursula P]]  | 
| - | [[Category: Song  | + | [[Category: Lehmann F]]  | 
| - | [[Category: Wilmanns  | + | [[Category: Song YH]]  | 
| - | [[Category: Zou  | + | [[Category: Wilmanns M]]  | 
| - | + | [[Category: Zou P]]  | |
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Current revision
Structure of the yeast YHH6 SH3 domain
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