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2ca6

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==MIRAS STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS==
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<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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==MIRAS structure determination from hemihedrally twinned crystals==
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<StructureSection load='2ca6' size='340' side='right'caption='[[2ca6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k5d|1k5d]], [[1k5g|1k5g]], [[1yrg|1yrg]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://pdbe.org/2ca6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [https://pdbe.org/2ca6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO]] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.
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[https://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ca6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cbs 356]]
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[[Category: Large Structures]]
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[[Category: Hillig, R C]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Renault, L]]
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[[Category: Hillig RC]]
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[[Category: Gap]]
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[[Category: Renault L]]
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[[Category: Gtpase activation]]
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[[Category: Gtpase-activating protein]]
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[[Category: Hemihedral twinning]]
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[[Category: Leucine-rich repeat protein]]
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[[Category: Lrr]]
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[[Category: Merohedral twinning]]
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[[Category: Merohedry]]
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[[Category: Nuclear transport]]
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[[Category: Rangap]]
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[[Category: Rna1p]]
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[[Category: Signaling activator]]
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[[Category: Signaling protein]]
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[[Category: Signaling regulator]]
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Current revision

MIRAS structure determination from hemihedrally twinned crystals

PDB ID 2ca6

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