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2afa

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[[Image:2afa.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of putative NAG isomerase from Salmonella typhimurium==
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|PDB= 2afa |SIZE=350|CAPTION= <scene name='initialview01'>2afa</scene>, resolution 2.15&Aring;
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<StructureSection load='2afa' size='340' side='right'caption='[[2afa]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[2afa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AFA FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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|GENE= yihS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00249 AGE]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2afa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afa OCA], [https://pdbe.org/2afa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2afa RCSB], [https://www.ebi.ac.uk/pdbsum/2afa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2afa ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2afa TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2afa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afa OCA], [http://www.ebi.ac.uk/pdbsum/2afa PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2afa RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/SQUS_SALTY SQUS_SALTY] Catalyzes the isomerization of sulfoquinovose (SQ) to 6-deoxy-6-sulfo-D-fructose (SF) (By similarity). In vitro, can also catalyze the interconversion of mannose, fructose and glucose, but has extremely low activity with glucose.[HAMAP-Rule:MF_00998]<ref>PMID:18328504</ref>
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'''Crystal Structure of putative NAG isomerase from Salmonella typhimurium'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2AFA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFA OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afa_consurf.spt"</scriptWhenChecked>
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[[Category: Salmonella typhimurium]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Burley, S K.]]
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</jmolCheckbox>
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[[Category: Kumaran, D.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2afa ConSurf].
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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<div style="clear:both"></div>
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[[Category: Swaminathan, S.]]
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== References ==
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[[Category: alpha/alpha-fold]]
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<references/>
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[[Category: dimer-of-trimer]]
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__TOC__
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[[Category: nag isomerase]]
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</StructureSection>
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[[Category: new york structural genomix research consortium]]
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[[Category: Large Structures]]
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[[Category: nysgxrc]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: protein structure initiative]]
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[[Category: Burley SK]]
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[[Category: psi]]
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[[Category: Kumaran D]]
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[[Category: renin-binding protein]]
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[[Category: Swaminathan S]]
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[[Category: structural genomic]]
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[[Category: t1489]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:20:10 2008''
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Current revision

Crystal Structure of putative NAG isomerase from Salmonella typhimurium

PDB ID 2afa

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