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2ew2

From Proteopedia

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[[Image:2ew2.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis==
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|PDB= 2ew2 |SIZE=350|CAPTION= <scene name='initialview01'>2ew2</scene>, resolution 2.00&Aring;
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<StructureSection load='2ew2' size='340' side='right'caption='[[2ew2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2ew2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Entfa Entfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EW2 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|GENE=
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08546 ApbA_C], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02558 ApbA], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK12921 PRK12921]</span>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [http://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [https://pdbe.org/2ew2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ew2 ProSAT], [https://www.topsan.org/Proteins/MCSG/2ew2 TOPSAN]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis'''
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[[https://www.uniprot.org/uniprot/Q831Q5_ENTFA Q831Q5_ENTFA]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).[RuleBase:RU003776]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2EW2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW2 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ew2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ew2 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: 2-dehydropantoate 2-reductase]]
[[Category: 2-dehydropantoate 2-reductase]]
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[[Category: Enterococcus faecalis]]
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[[Category: Entfa]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Clancy, S.]]
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[[Category: Clancy, S]]
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[[Category: Collart, F.]]
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[[Category: Collart, F]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Kim, Y.]]
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[[Category: Kim, Y]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Moy, S.]]
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[[Category: Moy, S]]
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[[Category: Zhou, M.]]
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[[Category: Zhou, M]]
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[[Category: alpha-beta structure]]
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[[Category: Alpha-beta structure]]
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[[Category: alpha-structure]]
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[[Category: Alpha-structure]]
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[[Category: mcsg]]
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[[Category: Mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: Oxidoreductase]]
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[[Category: protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:23:15 2008''
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Current revision

Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis

PDB ID 2ew2

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