2gow

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[[Image:2gow.gif|left|200px]]
 
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{{Structure
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==Solution structure of BC059385 from Homo sapiens==
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|PDB= 2gow |SIZE=350|CAPTION= <scene name='initialview01'>2gow</scene>
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<StructureSection load='2gow' size='340' side='right'caption='[[2gow]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2gow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GOW FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= UBL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gow OCA], [https://pdbe.org/2gow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gow RCSB], [https://www.ebi.ac.uk/pdbsum/2gow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gow ProSAT], [https://www.topsan.org/Proteins/CESG/2gow TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01814 NTGP5]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gow OCA], [http://www.ebi.ac.uk/pdbsum/2gow PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2gow RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/UBL3_HUMAN UBL3_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2gow_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gow ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The protein Bc059385, whose solution structure is reported here, is the human representative of a recently identified family of membrane-anchored ubiquitin-fold (MUB) proteins. Analysis of their similarity to ubiquitin indicates that homologous amino acid residues in MUBs form a hydrophobic surface very similar to the recognition patch surrounding Ile-44 in ubiquitin. This suggests that MUBs may interact with proteins containing an alpha-helical motif similar to those of some ubiquitin binding domains. A disordered loop common to MUBs may also provide a second protein interaction site. From the available data, it is probable that this protein is prenylated and associated with the membrane. With &lt;20% identity to ubiquitin, the MUB family further expands the sequence space that maps to the beta-grasp fold, and adds membrane localization to its list of functional roles.
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'''Solution structure of BC059385 from Homo sapiens'''
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Solution structure of a membrane-anchored ubiquitin-fold (MUB) protein from Homo sapiens.,de la Cruz NB, Peterson FC, Lytle BL, Volkman BF Protein Sci. 2007 Jul;16(7):1479-84. Epub 2007 Jun 13. PMID:17567738<ref>PMID:17567738</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2GOW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOW OCA].
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<div class="pdbe-citations 2gow" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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[[Category: Lytle BL]]
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[[Category: Cruz, N B.de la.]]
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[[Category: Peterson FC]]
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[[Category: Lytle, B L.]]
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[[Category: Volkman BF]]
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[[Category: Peterson, F C.]]
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[[Category: De la Cruz NB]]
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[[Category: Volkman, B F.]]
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[[Category: bc059385]]
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[[Category: center for eukaryotic structural genomic]]
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[[Category: cesg]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:27:12 2008''
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Current revision

Solution structure of BC059385 from Homo sapiens

PDB ID 2gow

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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