2gp4

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[[Image:2gp4.gif|left|200px]]
 
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{{Structure
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==Structure of [FeS]cluster-free Apo Form of 6-Phosphogluconate Dehydratase from Shewanella oneidensis==
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|PDB= 2gp4 |SIZE=350|CAPTION= <scene name='initialview01'>2gp4</scene>, resolution 2.49&Aring;
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<StructureSection load='2gp4' size='340' side='right'caption='[[2gp4]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[2gp4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_oneidensis_MR-1 Shewanella oneidensis MR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GP4 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydratase Phosphogluconate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.12 4.2.1.12] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
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|GENE= edd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70863 Shewanella oneidensis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK09054 PRK09054], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0129 IlvD]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gp4 OCA], [https://pdbe.org/2gp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gp4 RCSB], [https://www.ebi.ac.uk/pdbsum/2gp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gp4 ProSAT]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gp4 OCA], [http://www.ebi.ac.uk/pdbsum/2gp4 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2gp4 RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/Q8EEA0_SHEON Q8EEA0_SHEON] Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.[HAMAP-Rule:MF_02094]
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'''Structure of [FeS]cluster-free Apo Form of 6-Phosphogluconate Dehydratase from Shewanella oneidensis'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2GP4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shewanella_oneidensis Shewanella oneidensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GP4 OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gp/2gp4_consurf.spt"</scriptWhenChecked>
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[[Category: Phosphogluconate dehydratase]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Shewanella oneidensis]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gp4 ConSurf].
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[[Category: Schormann, N.]]
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<div style="clear:both"></div>
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[[Category: Symersky, J.]]
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__TOC__
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[[Category: c-terminal domain mainly beta-sheet (trefoil-like)]]
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</StructureSection>
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[[Category: n-terminal domain largely alpha-helical]]
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[[Category: Large Structures]]
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[[Category: protein structure initiative]]
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[[Category: Shewanella oneidensis MR-1]]
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[[Category: psi]]
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[[Category: Schormann N]]
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[[Category: secsg]]
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[[Category: Symersky J]]
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[[Category: southeast collaboratory for structural genomic]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:27:13 2008''
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Current revision

Structure of [FeS]cluster-free Apo Form of 6-Phosphogluconate Dehydratase from Shewanella oneidensis

PDB ID 2gp4

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