This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2gs8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (19:15, 10 March 2021) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2gs8.gif|left|200px]]
 
-
{{Structure
+
==Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes==
-
|PDB= 2gs8 |SIZE=350|CAPTION= <scene name='initialview01'>2gs8</scene>, resolution 1.50&Aring;
+
<StructureSection load='2gs8' size='340' side='right'caption='[[2gs8]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
+
<table><tr><td colspan='2'>[[2gs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_(serotype_1_/_m1_gas) Streptococcus pyogenes (serotype 1 / m1 gas)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GS8 FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
|GENE= mvaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160490 Streptococcus pyogenes M1 GAS])
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3407 MVD1], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08544 GHMP_kinases_C]</span>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mvaD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160490 Streptococcus pyogenes (serotype 1 / M1 GAS)])</td></tr>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gs8 OCA], [http://www.ebi.ac.uk/pdbsum/2gs8 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2gs8 RCSB]</span>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gs8 OCA], [https://pdbe.org/2gs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2gs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gs8 ProSAT], [https://www.topsan.org/Proteins/MCSG/2gs8 TOPSAN]</span></td></tr>
-
}}
+
</table>
-
 
+
== Evolutionary Conservation ==
-
'''Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes'''
+
[[Image:Consurf_key_small.gif|200px|right]]
-
 
+
Check<jmol>
-
 
+
<jmolCheckbox>
-
==About this Structure==
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gs8_consurf.spt"</scriptWhenChecked>
-
2GS8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_m1_gas Streptococcus pyogenes m1 gas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS8 OCA].
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Single protein]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Streptococcus pyogenes m1 gas]]
+
</jmolCheckbox>
-
[[Category: Clancy, S.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gs8 ConSurf].
-
[[Category: Cuff, M E.]]
+
<div style="clear:both"></div>
-
[[Category: Joachimiak, A.]]
+
__TOC__
-
[[Category: Li, H.]]
+
</StructureSection>
-
[[Category: MCSG, Midwest Center for Structural Genomics.]]
+
[[Category: Large Structures]]
-
[[Category: mcsg]]
+
[[Category: Clancy, S]]
-
[[Category: mevalonate pyrophosphate decarboxylase]]
+
[[Category: Cuff, M E]]
-
[[Category: midwest center for structural genomic]]
+
[[Category: Joachimiak, A]]
-
[[Category: protein structure initiative]]
+
[[Category: Li, H]]
-
[[Category: psi]]
+
[[Category: Structural genomic]]
-
[[Category: streptococcus pyogene]]
+
[[Category: Lyase]]
-
[[Category: structural genomic]]
+
[[Category: Mcsg]]
-
 
+
[[Category: Mevalonate pyrophosphate decarboxylase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:27:25 2008''
+
[[Category: PSI, Protein structure initiative]]
 +
[[Category: Streptococcus pyogene]]

Current revision

Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes

PDB ID 2gs8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gs8"
Personal tools