2gwn

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[[Image:2gwn.gif|left|200px]]
 
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{{Structure
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==The structure of putative dihydroorotase from Porphyromonas gingivalis.==
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|PDB= 2gwn |SIZE=350|CAPTION= <scene name='initialview01'>2gwn</scene>, resolution 1.85&Aring;
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<StructureSection load='2gwn' size='340' side='right'caption='[[2gwn]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[2gwn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_W83 Porphyromonas gingivalis W83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GWN FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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|GENE= pyrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=837 Porphyromonas gingivalis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01318 DHOase_IIb], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK09236 PRK09236]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gwn OCA], [https://pdbe.org/2gwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gwn RCSB], [https://www.ebi.ac.uk/pdbsum/2gwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gwn ProSAT], [https://www.topsan.org/Proteins/MCSG/2gwn TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gwn OCA], [http://www.ebi.ac.uk/pdbsum/2gwn PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2gwn RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/Q7MVW1_PORGI Q7MVW1_PORGI] Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.[ARBA:ARBA00002368]
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'''The structure of putative dihydroorotase from Porphyromonas gingivalis.'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2GWN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GWN OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gw/2gwn_consurf.spt"</scriptWhenChecked>
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[[Category: Porphyromonas gingivalis]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Borovilos, M.]]
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</jmolCheckbox>
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[[Category: Cuff, M E.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gwn ConSurf].
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[[Category: Joachimiak, A.]]
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<div style="clear:both"></div>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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__TOC__
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[[Category: Moy, S.]]
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</StructureSection>
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[[Category: dihydroorotase]]
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[[Category: Large Structures]]
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[[Category: mcsg]]
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[[Category: Porphyromonas gingivalis W83]]
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[[Category: midwest center for structural genomic]]
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[[Category: Borovilos M]]
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[[Category: porphyromonas gingivali]]
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[[Category: Cuff ME]]
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[[Category: protein structure initiative]]
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[[Category: Joachimiak A]]
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[[Category: psi]]
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[[Category: Moy S]]
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[[Category: structural genomic]]
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[[Category: zinc-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:27:53 2008''
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Current revision

The structure of putative dihydroorotase from Porphyromonas gingivalis.

PDB ID 2gwn

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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