2e7v
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of SEA domain of transmembrane protease from Mus musculus== | ==Crystal structure of SEA domain of transmembrane protease from Mus musculus== | ||
| - | <StructureSection load='2e7v' size='340' side='right' caption='[[2e7v]], [[Resolution|resolution]] 1.92Å' scene=''> | + | <StructureSection load='2e7v' size='340' side='right'caption='[[2e7v]], [[Resolution|resolution]] 1.92Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e7v]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2e7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E7V FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7v OCA], [https://pdbe.org/2e7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e7v RCSB], [https://www.ebi.ac.uk/pdbsum/2e7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7v ProSAT], [https://www.topsan.org/Proteins/RSGI/2e7v TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TM11D_MOUSE TM11D_MOUSE] May play some biological role in the host defense system on the mucous membrane, independently of, or in cooperation with other substances in airway mucous or bronchial secretions (By similarity). Isoform 2 may play a key role in regulating adrenal proliferation by specifically cleaving N-POMC. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7v_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7v_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7v ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Chen | + | [[Category: Mus musculus]] |
| - | [[Category: Hori-Takemoto | + | [[Category: Chen L]] |
| - | [[Category: Kishishita | + | [[Category: Hori-Takemoto C]] |
| - | [[Category: Liu | + | [[Category: Kishishita S]] |
| - | [[Category: Murayama | + | [[Category: Liu ZJ]] |
| - | + | [[Category: Murayama K]] | |
| - | [[Category: Shirozu | + | [[Category: Shirozu M]] |
| - | [[Category: Wang | + | [[Category: Wang BC]] |
| - | [[Category: Xie | + | [[Category: Xie Y]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of SEA domain of transmembrane protease from Mus musculus
| |||||||||||
Categories: Large Structures | Mus musculus | Chen L | Hori-Takemoto C | Kishishita S | Liu ZJ | Murayama K | Shirozu M | Wang BC | Xie Y | Yokoyama S
