2hqe

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[[Image:2hqe.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of human P100 Tudor domain: Large fragment==
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|PDB= 2hqe |SIZE=350|CAPTION= <scene name='initialview01'>2hqe</scene>, resolution 2.00&Aring;
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<StructureSection load='2hqe' size='340' side='right'caption='[[2hqe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2hqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQE FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE= SND1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqe OCA], [https://pdbe.org/2hqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqe RCSB], [https://www.ebi.ac.uk/pdbsum/2hqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqe ProSAT], [https://www.topsan.org/Proteins/SECSG/2hqe TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00175 SNc], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00567 TUDOR]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqe OCA], [http://www.ebi.ac.uk/pdbsum/2hqe PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2hqe RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
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== Evolutionary Conservation ==
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'''Crystal structure of human P100 Tudor domain: Large fragment'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqe_consurf.spt"</scriptWhenChecked>
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2HQE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQE OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqe ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Cheng, C.]]
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[[Category: Cheng C]]
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[[Category: Liu, Z J.]]
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[[Category: Liu ZJ]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Shah N]]
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[[Category: Shah, N.]]
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[[Category: Silvennoinen O]]
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[[Category: Silvennoinen, O.]]
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[[Category: Wang BC]]
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[[Category: Wang, B C.]]
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[[Category: Xu H]]
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[[Category: Xu, H.]]
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[[Category: Yang J]]
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[[Category: Yang, J.]]
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[[Category: Zhao M]]
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[[Category: Zhao, M.]]
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[[Category: human]]
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[[Category: large fragment]]
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[[Category: p100 tudor domain]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: secsg]]
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[[Category: southeast collaboratory for structural genomic]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:29:42 2008''
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Current revision

Crystal structure of human P100 Tudor domain: Large fragment

PDB ID 2hqe

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