2if2

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[[Image:2if2.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.==
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|PDB= 2if2 |SIZE=350|CAPTION= <scene name='initialview01'>2if2</scene>, resolution 3.00&Aring;
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<StructureSection load='2if2' size='340' side='right'caption='[[2if2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2if2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IF2 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dephospho-CoA_kinase Dephospho-CoA kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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|GENE= coaE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02022 DPCK]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2if2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2if2 OCA], [https://pdbe.org/2if2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2if2 RCSB], [https://www.ebi.ac.uk/pdbsum/2if2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2if2 ProSAT], [https://www.topsan.org/Proteins/NESGC/2if2 TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2if2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2if2 OCA], [http://www.ebi.ac.uk/pdbsum/2if2 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2if2 RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/COAE_AQUAE COAE_AQUAE] Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity).
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'''Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2IF2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/2if2_consurf.spt"</scriptWhenChecked>
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[[Category: Aquifex aeolicus]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Dephospho-CoA kinase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Acton, T B.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2if2 ConSurf].
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[[Category: Baran, M.]]
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<div style="clear:both"></div>
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[[Category: Cunningham, K.]]
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__TOC__
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[[Category: Fang, Y.]]
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</StructureSection>
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[[Category: Forouhar, F.]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Hunt, J F.]]
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[[Category: Large Structures]]
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[[Category: Hussain, A.]]
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[[Category: Acton TB]]
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[[Category: Hussain, M.]]
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[[Category: Baran M]]
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[[Category: Liu, J.]]
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[[Category: Cunningham K]]
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[[Category: Ma, L C.]]
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[[Category: Fang Y]]
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[[Category: Montelione, G T.]]
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[[Category: Forouhar F]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Hunt JF]]
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[[Category: Rost, B.]]
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[[Category: Hussain A]]
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[[Category: Seetharaman, J.]]
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[[Category: Hussain M]]
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[[Category: Tong, L.]]
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[[Category: Liu J]]
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[[Category: Wu, M.]]
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[[Category: Ma LC]]
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[[Category: Xiao, R.]]
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[[Category: Montelione GT]]
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[[Category: alpha-beta protein]]
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[[Category: Rost B]]
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[[Category: nesg]]
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[[Category: Seetharaman J]]
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[[Category: northeast structural genomics consortium]]
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[[Category: Tong L]]
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[[Category: protein structure initiative]]
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[[Category: Wu M]]
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[[Category: psi-2]]
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[[Category: Xiao R]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:31:57 2008''
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Current revision

Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.

PDB ID 2if2

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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